Living Legends

Thomas Starzl Memorial Lecture

Sir Roy Y. Calne (United Kingdom)
The Early Days of Transplantation; Collaboration with Tom Starzl and a Short Summary of Recent Developments in Gene Therapy for Diabetes

5 September (Wednesday)
10:30-11:00 Room A+B+C

Sir Roy Yorke Calne, FRS, is a surgeon and pioneer in organ transplantation since 1959. He was the first to develop and use Azathioprine, Cyclosporine, Rapamycin and Campath 1H. He started a kidney transplant programme in Cambridge in 1965 and performed the first liver transplantation operation in Europe in 1968. He performed the world's first liver, heart, and lung transplant in 1987 and did the first intestinal transplant in the U.K. in 1992, and the first successful combined stomach, intestine, pancreas, liver, and kidney cluster transplant in 1994.

Sir Roy was Harkness Fellow at Harvard Medical School from 1960-61 and Professor of Surgery at Cambridge University between 1965 and 1998. He was awarded the 2012 Lasker-DeBakey Clinical Medical Research Award for the development of liver transplantation. In 2014 he was awarded the Pride of Britain Award for Lifetime Achievement.

Sir Roy works at the National University of Singapore, involved in the development of gene and stem cell therapy for the treatment of diabetes.


Dr John L. Cameron (United States)
Personal Experience with Over 2000 Pancreaticoduodenectomies
6 September (Thursday)
10:30-11:00 Room A+B+C

John L. Cameron, M.D, the Alfred Blalock Distinguished Service Professor of Surgery at The Johns Hopkins University School of Medicine. For nineteen years he served as the Chief of Surgery at The Johns Hopkins Hospital. Dr Cameron obtained his undergraduate degree from Harvard University in 1958 and his medical degree from The Johns Hopkins University School of Medicine in 1962. All of his training in General and Thoracic Surgery was obtained at The Johns Hopkins University School of Medicine.

Dr Cameron has had a long-standing interest in alimentary tract diseases, and specifically pancreatic cancer. He has operated upon more patients with pancreatic cancer, and done more Whipple resections than any other surgeon in the world. He has been a leader in Alimentary Tract Surgery for many years. National leadership positions held include being President of the Society for Surgery of the Alimentary Tract, President of the Southern Surgical Association, President of the Society of Clinical Surgery, President of the Society of Surgical Chairman, President of the Halsted Society, and President of the American Surgical Association. And most recently he was President of the American College of Surgeons.


Dr Sheung Tat Fan (Hong Kong)
Continued Improvement of Liver Surgery
7 September (Friday)
10:30-11:00 Room A+B+C

Professor Sheung Tat Fan is currently the Director of Liver Surgery & Transplant Centre at Hong Kong Sanatorium & Hospital, Hong Kong and Emeritus Professor of The University of Hong Kong.

Fellow of four surgical colleges and holder of four doctorate degrees, Professor Fan researched and published extensively on diseases that are commonly seen in Asia, namely, hepatocellular carcinoma, hepatitis B, cirrhosis, intrahepatic stones and acute biliary pancreatitis. He has authored more than 800 articles to date.

According to ISI Essential Science Indicators, Professor Fan ranks top 1% scientists in clinical medicine by citations in the world.

In 1991, Professor Fan performed the first successful liver transplant in Hong Kong. In 1996, he pioneered the technique of adult-to-adult living donor liver transplantation using a right liver graft. This innovative procedure helped ease the continuing problem of organ shortage in adult patients. The operation is now widely adopted and is regarded as a major breakthrough in the history of liver transplantation.

In 2005, Professor Fan was elected as an Academician of Chinese Academy of Engineering, China. In 2008, he was awarded the TTS-Genzyme Award for Innovation in Surgery and Technology by The Transplantation Society.


Keynote Speakers

Dr Javier Lendoire (Argentina)
Management of Intrahepatic Biliary Cysts
5 September (Wednesday)
13:15-13:45 Room A

Javier C Lendoire, MD, Ph.D, graduated with the Honor Degree at the University of Buenos Aires. His general surgical training was completed at the Hospital Espanol of Buenos Aires. In 1989, he was awarded with the Rotary Foundation Scholarship for International Understanding and began his training in Hepatobiliary Surgery and Liver Transplantation at the Transplant Division of the University of Pittsburgh in charge of Thomas Starzl.

In 1993 Javier Lendoire as Vice Chairman, opened with Oscar Imventarza as Chairman, the first Public Adult Liver Transplant Program of Argentina in the Hospital Dr C Argerich of Buenos Aires. Also they developed the first Liver Transplant Program of the Litoral Region located in Formosa City.

In 2003 he received his Ph.D from the University of Buenos Aires and in 2007 he was appointed Professor of Surgery at the same University.

Dr Lendoire is founding member and Past-President of the Argentine Society of Transplantation, Council Member of the Argentine Chapter of the IHPBA (CA-IHPBA) since 2003 and President since 2015. He served as President of the AHPBA and is a member of the Scientific Committee of the IHPBA since 2008. Dr Lendoire lives in Buenos Aires with his wife Luz de Undurraga and their 4 children, Mateo, Delfina, Candelaria and Lucila.


Professor Andrea Frilling (United Kingdom)
Advances in the Multidisciplinary Management of NE Liver Mets
5 September (Wednesday)
13:15-13:45 Room B

Professor Andrea Frilling, MD, PhD is affiliated as Professor of Surgery and Chair in Endocrine Surgery with the Imperial College London, UK. After her general surgical training she specialized in endocrine surgery, hepato-pancreato-biliary surgery and oncologic abdominal surgery. She has authored ~ 400 peer reviewed scientific papers and contributed to ~20 books on diverse subjects on endocrine and hepato-pancreato-biliary surgery. She is a Fellow of the Royal College of Surgeons, of the American College of Surgeon, the European Board of Endocrine Surgery and of the European Board of Hepato-Pancreato-Biliary-Surgery. She sits on the advisory boards of a number of international cancer committees. She has received numerous awards including the von Langenbeck Prize, the most prestigious Award of the German Surgical Society, The Endocrine Society and Pfizer, Inc. International Award for Excellence in Published Clinical Research, and the Eminent Scientist of the Year 2012 award. She is a council member of several medical societies including ESA, IHPBA, E-AHPBA and ENETS /UKINETS and reviewer for high-quality scientific journals such as Annals of Surgery, British Journal of Surgery, Lancet Oncology and Gut.

Professor Frilling’s original research investigated the genetic background of hereditary endocrine tumours. She was a member of the international consortium which discovered RET proto-oncogene mutations as a hereditary background of medullary thyroid cancer and introduced prophylactic thyroidectomy for RET gene carriers in the treatment concept of this disease. In cooperation with her US partners she developed a three-gene signature allowing discrimination of follicular adenoma from follicular cancer on thyroid biopsy. Her focus at Imperial is on multimodal management of patients with neuroendocrine tumours including a number of new biomarker-based approaches. In 2012 she organised an International Consensus Conference on Neuroendocrine Liver Metastases and developed guidelines including an algorithm for their management published in Lancet Oncology. She is primary investigator for several commercial and academic clinical trials in hepato-pancreato-biliary tumours. Her laboratory work is concentrated on novel liquid biomarker discovery and their validation during the patient journey Together with an interdisciplinary group at the Imperial she successfully accomplished the ENETS certification programme for Centres of Excellence for Management of Gastro-Entero-Pancreatic Neuroendocrine Tumours with an emphasis on early diagnosis, multimodal treatment and translational research. She has generated substantial funding including major grants from the German Research Society, Dr. Mildred Scheel Foundation, NIHR, MRC, CRUK and EU FP7. Her Chair in Endocrine Surgery is underpinned by a €1.7 million grant of the Dr Heinz-Horst Deichmann Foundation for research in genomics, metabonomics and integrative biology of neuroendocrine tumours.


Professor John Neoptolemos (United Kingdom)
ESPAC Trials – Overview and Impact of Clinical Care
5 September (Wednesday)
13:15-13:45 Room C

John Neoptolemos, MA, MB, BChir, MD, FRCS, FMedSci, trained at the University of Cambridge with a double degree in Natural Sciences and Philosophy followed by clinical training at Guy’s Hospital in London. He is Professor of Surgery at the University of Heidelberg moving from Liverpool University where he held the Chair of Surgery from 1996 until 2017. As Chairman of ESPAC he successfully led the ESPAC -1, 3 and 4 trials, the results of which have been adopted as guidelines for the treatment of potentially curable pancreatic cancer around the world. As Director, he received the Freedom of the City of Liverpool in 2011 for the Liverpool Cancer Research UK Centre. In 2007, he established the NIHR Liverpool Pancreas Biomedical Research Unit (Scientific Director), the NIHR and Cancer research UK Liverpool Experimental Cancer Medicine Centre (Deputy Director), and the Liverpool Clinical Trials and Cancer Research UK Cancer Trials Units (Director). In 2012 he was made an Honorary Member of the German Society of Surgery. In 2013 the Pancreas Unit won the Acute Services Sector Health Services Journal National Award. In 2013 he received a Life Time Achievement Award from the European Pancreatic Club at its 45th Meeting in Zurich. In 2014 he was made an Honorary Member of the Hungary Society of Surgery and also an Honorary Professor of Nanjing Medical University. He was awarded Hirschberg Award for Pancreatic Cancer, American Pancreatic Association in 2005 and the Ruth Brufsky Award for Pancreas Cancer Research in 2017. Presently he is on the Medical Advisory Board for Pancreas Cancer UK. He was elected Fellow of the Academy of Medical Sciences in 2007 and NIHR Senior Investigator in 2011.


Dr Maria B. Majella Doyle (United States)
Challenges in Evaluating Surgical Innovation
6 September (Thursday)
13:15-13:45 Room A

Maria B. Majella Doyle, M.D., M.B.A., F.A.C.S., is Associate Professor of Surgery, Director of the HPB Fellowship Program, and Director of Liver Transplant in the Division of General Surgery, Section of Abdominal Transplantation, at Washington University in St. Louis, as well as the Director of the Pediatric Liver Transplant Program at St. Louis Children’s Hospital.

Dr. Maria Doyle received her Bachelor of Arts Degree at Trinity College in Dublin Ireland before completion of medical school at the Royal College of Surgeons in Ireland. She then completed her surgical residency in the Irish General Surgical Training Program at the Royal College of Surgeons before completing a Research Fellowship in the Department of Academic Surgery at Cork University in Cork, Ireland. She completed a Clinical Fellowship in Abdominal Organ Transplant at Washington University School of Medicine in St. Louis, Missouri and was subsequently recruited as a member of the Abdominal Organ Transplant and Hepatobiliary Surgery team. Her interests at the university are focused on adult and pediatric hepatobiliary and pancreatic surgery as well as liver and kidney transplant. She focuses her clinical research interests on clinical outcomes, hepatocellular carcinoma, liver transplantation, and donor management.


Dr Steven Strasberg (United States)
Reporting the Outcome of Treatment of Biliary Injuries
6 September (Thursday)
13:15-13:45 Room B

Steven M Strasberg MD FACS FRCS (C) FRCS(Ed) is Pruett Professor of Surgery at Washington University in St Louis, Barnes-Jewish Hospital, and Siteman Cancer Center where he has worked since 1992. His area of interest is Hepato-Pancreato-Biliary Surgery. Prior to coming to St Louis he was Professor of Surgery at University of Toronto where he taught and practiced for more than 15 years. He has published extensively on technical aspects of liver, biliary and pancreatic surgery, surgical innovation, standardization and safety in surgery, and on the surgical treatment of malignant tumors of these organs. He has a specific interests in “safe cholecystectomy” particularly the prevention of bile duct injuries and their treatment and also in improvement of reporting of surgical observational trials by standardized tabular reporting (STR). He is a past president of the American Hepato-Pancreato-Biliary Association (AHPBA) and has served twice on council of IHPBA. He is a member of the editorial board of Journal of the American College of Surgeons, the Journal of Gastrointestinal Surgery and JHPBS. He holds honorary membership in ESA, JHPBS, and the Argentine Academy of Surgery. He is a recipient of the IHPBA Lifetime Achievement Award (2012) and AHPBA Distinguished Service Award (2014). CV includes 300 peer reviewed papers and 45 book chapters.


Professor Go Wakabayashi (Japan)
Status of Minimally Invasive Surgery in 2018
6 September (Thursday)
13:15-13:45 Room C

Go Wakabayashi, MD, PhD, FACS, earned his degrees from Keio University School of Medicine, Tokyo Japan. He trained at Department of Surgery at Massachusetts General Hospital and Harvard Medical School. After working as an Assistant Professor at Department of Surgery, Keio University School of Medicine, he got appointed as Professor and Chairman of Department of Surgery at Iwate Medical University School of Medicine in 2005. From April 2015, he was recruited as Director of Center for Advanced Treatment of HPB Disease, Chief of Surgical Services, and Deputy Director at Ageo Central General Hospital, which is a flagship hospital among 6,000 beds hospital complex near Tokyo. His expertise includes Hepato-Pancreatic Biliary Surgery, liver transplantation, and laparoscopic surgery. He has operated more than 150 cases of living liver transplantation and over 3000 cases of HPB surgery and laparoscopic surgery. His publications are over 300 peer review articles and book chapters related to HPB surgery, liver transplantation, and laparoscopic surgery. He was awarded Gold Medal of Video Olympics at The World Congress of Endoscopic Surgery 1996. He also practices conventional HPB surgery and aggressive surgery as well. He holds numerous important positions in Japanese and international surgical societies.